monofloral vs multifloral manuka honey

Monofloral vs Multifloral Manuka Honey: A Comparison of Antibacterial Properties and Effects on Antibiotic-Resistant Wound Infections


In the world of natural remedies, honey has long been recognized for its healing properties. One type of honey that has gained significant attention in recent years is manuka honey. Manuka honey is derived from the nectar of the manuka tree (Leptospermum scoparium) and is known for its unique antibacterial properties. However, there is also a debate about the effectiveness of manuka honey compared to other types of honey, such as multifloral honey. In this article, we will explore the differences between monofloral and multifloral manuka honey and their potential effects on antibiotic-resistant wound-infecting bacteria.

Monofloral Manuka Honey

The Production of Manuka Honey

Manuka honey is produced by bees that collect nectar from the flowers of the manuka tree. The resulting honey has a distinct flavor and aroma, which is often described as earthy, herbaceous, and slightly bitter. The concentration of manuka honey can vary depending on the region and the time of year, as well as other factors such as weather conditions and beekeeping practices.

Antibacterial Properties of Manuka Honey

One of the reasons manuka honey is highly valued is its antibacterial properties. Manuka honey contains natural compounds, such as methylglyoxal (MGO), dihydroxyacetone (DHA), and hydrogen peroxide, which have been found to inhibit the growth of bacteria. These compounds are believed to work together to create a synergistic effect, making manuka honey a potent antibacterial agent. The level of antibacterial activity in manuka honey is often measured using the Unique Manuka Factor (UMF), which indicates the concentration of MGO in the honey.

Scientific Studies on Monofloral Manuka Honey

Several scientific studies have been conducted to evaluate the antibacterial efficacy of monofloral manuka honey. In a study published in the Journal of Antimicrobial Chemotherapy, researchers tested the activity of various honey samples against antibiotic-resistant bacteria, including Acinetobacter baumannii, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. The study found that manuka honey had significant antibacterial activity against these bacteria, even at low concentrations.

Another study published in Frontiers in Microbiology investigated the antibiofilm effects of manuka honey on MRSA and VRE biofilms. The researchers found that manuka honey was able to inhibit the formation and growth of biofilms, which are communities of bacteria that can form on surfaces and contribute to the development of chronic wounds.

Multifloral Manuka Honey

What is Multifloral Manuka Honey?

Multifloral manuka honey, also known as polyfloral or blended manuka honey, is produced by bees that collect nectar from a variety of plant sources, including manuka trees and other flowering plants. Unlike monofloral manuka honey, which is derived solely from the nectar of manuka trees, multifloral manuka honey is a combination of nectars from different plants.

Antibacterial Properties of Multifloral Manuka Honey

Although multifloral manuka honey may not have the same concentration of MGO as monofloral manuka honey, it still possesses antibacterial properties. The combination of different plant nectars in multifloral honey can contribute to its antimicrobial activity. Additionally, multifloral manuka honey may contain other bioactive compounds that have antibacterial effects.

Scientific Studies on Multifloral Manuka Honey

While there is limited research specifically on multifloral manuka honey, studies have shown that multifloral honey in general has antibacterial properties. A study published in the Journal of Applied Microbiology investigated the antimicrobial activity of various honey samples, including multifloral honey, against a range of bacteria. The study found that multifloral honey had significant antimicrobial activity against the tested bacteria, including S. aureus, Escherichia coli, and Pseudomonas aeruginosa.


In conclusion, both monofloral and multifloral manuka honey have been found to inhibit the growth of antibiotic-resistant wound-infecting bacteria. Monofloral manuka honey, with its high concentration of bioactive compounds, may have a more potent antibacterial effect. However, multifloral manuka honey, with its combination of nectars from different plants, also possesses antibacterial properties. Regardless of the type of manuka honey used, it is clear that honey, in general, can be an effective natural remedy for wound infections. Further research is needed to better understand the optimal use of manuka honey in wound care and to explore its potential applications in other areas of medicine.

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