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Artificial Sweeteners and Other Sugar Substitutes


In our quest to satisfy our sweet tooth, many of us turn to sugary snacks and drinks. However, consuming foods and beverages with high amounts of added sugar can lead to weight gain and increase the risk of serious health issues like diabetes and heart disease.

While some people try to avoid table sugar by using less processed sweeteners like honey and molasses, it’s important to note that these are still forms of added sugar and contribute to calorie intake.

To address this issue, many individuals turn to sugar substitutes, also known as artificial sweeteners. These alternatives taste sweet like sugar but have fewer or no calories. They are commonly found in various sugar-free or diet foods and drinks, including soft drinks, candy, and baked goods.

In this article, we will explore the pros and cons of sugar substitutes, their uses, safety, health benefits, and potential concerns.

Uses for Sugar Substitutes

Sugar substitutes come in different forms, with varying levels of sweetness. Some sugar substitutes are much sweeter than sugar, requiring only a small amount to sweeten foods and beverages. Others, known as sugar alcohols, are less sweet than sugar.

These sugar substitutes are commonly found in a wide range of foods and drinks labeled as sugar-free or diet. They can also be purchased separately in packets or containers for home use.

Safety of Sugar Substitutes

Government health agencies regulate the use of ingredients, including sugar substitutes, in food products. Before foods or drinks containing sugar substitutes can be sold, these agencies carefully evaluate the safety of the ingredients. In the United States, the Food and Drug Administration (FDA) allows the use of the following sugar substitutes:

  1. Acesulfame potassium (Sweet One, Sunett)
  2. Advantame
  3. Aspartame (NutraSweet, Equal)
  4. Neotame (Newtame)
  5. Saccharin (Sweet’N Low)
  6. Sucralose (Splenda)
  7. Luo han guo (Monk Fruit in the Raw)
  8. Purified stevia leaf extracts (Truvia, PureVia, others)

Other countries, such as those in the European Union, have a broader range of sugar substitute options than the United States.

The FDA also allows the use of sugar alcohols, such as sorbitol and xylitol, in food products. Sugar alcohols are not considered food additives by the agency.

Both the FDA and food safety agencies in other countries provide guidelines on the acceptable daily intake (ADI) of sugar substitutes. The ADI varies based on an individual’s weight and the specific type of sugar substitute used. It’s important to note that ADIs may differ between countries.

In general, artificial sweeteners are considered safe in limited amounts for healthy individuals, including pregnant women. However, there are certain situations where it is recommended to limit or avoid sugar substitutes:

  1. Individuals with phenylketonuria, a rare genetic disease, should avoid foods and drinks containing aspartame, as it can cause serious health problems.
  2. People with bowel diseases may experience flare-ups of symptoms when using sugar substitutes.

Dietary guidelines for Americans advise against giving sugar substitutes to children under 2 years old. More research is needed to determine the long-term health effects of sugar substitutes in children, as most studies have focused on adults.

Health Benefits Linked to Sugar Substitutes

Replacing added sugar with sugar substitutes can offer several potential health benefits, including:

  1. Reduced risk of tooth decay and cavities: Sugar substitutes do not contribute to tooth decay and can help protect dental health.
  2. Blood sugar management: Sugar substitutes do not raise blood sugar levels, making them suitable for individuals with diabetes or those trying to control their blood sugar.
  3. Weight management: For adults and children with overweight or obesity, sugar substitutes can be a useful tool in managing weight in the short term. Since sugar substitutes are low in calories or calorie-free, they can help reduce overall calorie intake. However, their long-term effectiveness in weight management is still uncertain. It’s important to prioritize a healthy diet and regular exercise for sustainable weight management.

Health Concerns Linked to Sugar Substitutes

There have been concerns regarding the safety of sugar substitutes and their potential health risks. However, health agencies have clarified that sugar substitutes do not cause serious health problems or increase the risk of cancer.

Some studies on the long-term, daily use of artificial sweeteners have suggested a possible link to a higher risk of stroke, heart disease, and overall mortality. However, it’s important to consider that other lifestyle factors or habits may contribute to these health risks, and more research is needed to establish a definitive connection.

Ongoing research is also investigating the potential effects of sugar substitutes on the gut and its communication with the brain. Scientists are exploring whether sugar substitutes impact cravings for sweets, hunger sensations, and blood sugar regulation.

Certain sugar substitutes, such as sugar alcohols, stevia, and luo han guo, may cause side effects like bloating, gas, and diarrhea. The severity of these symptoms varies from person to person.

To ensure safety, it is advisable to consume sugar substitutes in moderation and for short periods or occasional use. If you find yourself using sugar substitutes frequently throughout the day, it may be beneficial to reduce your intake.


Artificial sweeteners, or sugar substitutes, can be a helpful tool for reducing sugar consumption and managing weight in the short term. They are generally safe for healthy adults when used in moderation.

However, it’s crucial to be mindful of how sugar substitutes may influence your food and drink choices. They can alter your taste preferences, making it more challenging to appreciate the natural sweetness of foods and beverages. Adequate hydration can also become a challenge if your taste buds become accustomed to excessive sweetness.

While products made with sugar substitutes may seem like a healthier option, it’s essential to remember that whole foods, such as fruits and vegetables, provide a better balance of nutrients for overall health.

Incorporating artificial sweeteners into a healthy diet can help individuals enjoy sweetness without the unnecessary calories. However, it’s important to prioritize whole, nutritious foods and maintain a balanced lifestyle for optimal health.

– Mayo Clinic Staff. (n.d.). Artificial sweeteners and other sugar substitutes. Mayo Clinic. Retrieved from

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