Table of Contents
Introduction
Manuka Honey is a natural product derived from the insect Apis mellifera. It is a complex mixture with antimicrobial, antioxidant, and antidiabetic activity. With approximately 200 different compounds, Manuka Honey has gained attention for its potential health benefits. In this article, we will explore the antioxidant activity of a natural honey-based gel called ‘Bear Strength honey gel’ and its physiological and redox adjustments in healthy adult participants.
Antioxidant Activity of Manuka Honey
Manuka Honey contains flavonoids and phenolic acids, which are associated with its antioxidant capacity. These compounds contribute to its ability to donate hydrogen and chelate metallic ions, although the exact mechanism of its antioxidant activity remains unknown.
Study Design and Participants
The aim of the study was to assess the antioxidant activity of the Bear Strength honey gel and its effects on physiological and redox adjustments in healthy adult participants. The study included 20 participants (10 men and 10 women) who consumed 70 g of the honey-based gel daily for 14 consecutive days.
Physiological and Hematological Evaluations
Before and after the consumption of the honey-based gel, the participants’ physiological and hematological data were evaluated. This included measurements of weight, height, body mass index, body fat, waist-to-hip ratio, resting heart rate, blood pressure, and complete blood count.
Redox Biomarkers
The study also assessed the levels of five redox biomarkers: Glutathione (GSH), catalase (CAT), total antioxidant capacity (TAC), protein carbonyls (PCARBS), and thiobarbituric reactive substances (TBARS). These biomarkers provide insights into the participants’ redox status and oxidative stress levels.
Results
The results of the study revealed several interesting findings regarding the effects of the honey-based gel on the participants’ physiological and redox status.
Physiological Adjustments
The consumption of the honey-based gel led to a decrease in diastolic and mean arterial blood pressure, particularly in women. However, there were no significant changes observed in other physiological variables such as weight, height, body mass index, body fat, waist-to-hip ratio, resting heart rate, or complete blood count.
Redox Adjustments
In terms of redox adjustments, the consumption of the honey-based gel resulted in increased levels of glutathione (GSH) in both the total group and women. Total antioxidant capacity (TAC) was also increased in all groups after consumption. However, there were no significant changes observed in catalase (CAT) levels.
Oxidative Stress
The levels of thiobarbituric reactive substances (TBARS), a marker of oxidative stress, decreased in both the total group and women after consuming the honey-based gel. Additionally, protein carbonyls (PCARBS) levels were decreased specifically in the women’s group.
Conclusion
In conclusion, the present study demonstrated the potential positive effects of a honey-based gel on blood pressure and redox status in healthy adults, particularly in women. The consumption of the honey-based gel led to improvements in diastolic and mean arterial blood pressure, as well as increased levels of glutathione and total antioxidant capacity. Furthermore, oxidative stress markers such as TBARS and protein carbonyls were reduced after consuming the honey-based gel. These findings highlight the potential benefits of Manuka Honey in promoting cardiovascular health and redox balance.
